Under the tradename this substance is very well known as Nolvadex. This resource is a little out of line, because they are not anabolic - androgenic steroid. Tamoxifen belongs to the group of sex hormones and is known as the so-called. Antiestrogen. Normally it is used in the treatment of breast cancer of women. Tamoxifen can reverse an existing growth process of disease tissue and prevent new growth. The growth of certain tissues is activated, inter alia, the body's own hormone estrogen. This applies in particular to the mammary glands of both men and women, because there are a large number of estrogen receptors, which are in contact with estrogens, are in being in the blood. When estrogen levels are unusually high, it may cause an undesirable growth of mammary glands. However, this healthy women and men primarily affected. Antiestrogen Nolvadex blocks estrogen receptors in the affected tissues and thus prevents a concentration of estrogen receptors. Tamoxifen does not suppress flavor, but is only estrogenic antagonistou. Exceptional, but very serious problem of Nolvadex is that in some cases the level of estrogen decreases, but on the contrary, it may increase. Instead of reducing the production of estrogen leads to the stimulation site and the role of estrogen antagonist (opponent estrogen) may act as an agonist (On the other hand, helper). For still unknown reasons, in some cases greatly increase production (dehydroepiandrosterone), originating from the adrenal glands. As the forerunner in the production of steroid peripheral estrogen (and testosterone), estrogen levels rise, so the effect of tamoxifen binding to overshadow its central receptors. Nolvadex has a direct influence on the hypothalamus, while through increased secretion of gonadotropin promotes testosterone production in varlatech.V rare cases, there may be nausea, vomiting, flushing and abnormal vision. Women may experience menstrual disturbances, manifested weaker bleeding or its absence. In addition, women should not during the application of Tamoxifen pregnant. Also important is the fact that while Nolvadex may be administered contraceptive pills, because anti-estrogen nolvadex pills containing estrogen and adversely affect one another.
Nolvadex (tamoxifen citrate) is probably the most popular ancillary drug for male steroid users who wish to avoid the estrogen like effects caused by the use of anabolic steroids (e.g. gynecomastia). Nolvadex binds to estrogen receptors thus blocking the hormones action on target tissues and achieving an anti-estrogenic effect.
Also worth noting is the fact that Nolvadex is an estrogen agonist in the liver and is capable of mimicking estrogen in this organ. At first glance you may wonder why this could be considered a good thing, however, when you realize that estrogen positively effects HDL (good) cholesterol values in the liver its value in this instance becomes obvious. As you know, steroid use tends to suppress HDL levels and raise LDL levels significantly leading to increased cholesterol levels and cardiac risk. Adding Nolvadex may therefore form a protective function in this case, although it certainly does not save the liver from all the other hazards involved with the use of c-17 alpha alkylated orals.
Tamoxifen also has the ability to increase production of FSH (follicle stimulating hormone) and LH (luteinizing hormone) in the male body. A higher level of LH stimulates the Leydig cells in the testes to produce more testosterone therefore Nolvadex can actually have a positive influence on testosterone levels. This is particularly important when ending a cycle of steroid use, since most anabolic/androgenic steroids significantly reduce the production of natural testosterone. Adding Nolvadex can assist in returning testosterone levels to normal levels in most cases however, following longer cycles of stronger drugs the addition of HCG (a hormone which mimics LH) may be required to kick start the testes into action.
This needs to be done with care though since HCG also enhances the rate of aromatization in the testes (i.e. the conversion of testosterone to estrogen) and, in order to avoid unwanted side effects, anti- estrogens should not be discontinued until at least a couple of weeks after ceasing the use of HCG.
Men should typically take 10 to 30mg/day depending on the amount of steroid used and the length of cycle. Starting at a low dosage and working up is recommended in order to avoid taking more than is necessary.
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